The cast of Uncharted 2: Among Thieves in the style of My Little Pony: Friendship is Magic.
Drawn at the behest of my sister, who loves both (as do I).
(she runs www.nolannorthfan.com)
From left to right: Elena Fisher, Nathan Drake, Chloe Frazer, and Victor "Sully" Sullivan
The background is not mine; it's some Uncharted 2 concept art from here: [link]
UPDATE: Jacob Minkoff, a lead designer at Naughty Dog who worked on Uncharted 2, used this image in an awesome blog post about MLP:FiM! Check it out here: [link]
UPDATE2: Check this out, from Nolan North's book about the making of Uncharted 3: [link]
The dogs sure love their ponies. It's a dog and pony show!